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Today, 3-HO-PCP is almost exclusively distributed as a gray area research chemical by online vendors. Extremely little is known about its pharmacology, metabolism and toxicity in humans. Due to its sensitive dose-response, potential habit-forming properties, as well as unknown toxicity profile, it is strongly recommended that one use proper harm reduction practices if choosing to use this substance.
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BAY 38-7271 Originally synthesized by chemist Wayne E. Kenney, BAY 38-7271 (KN 38-7271) is a drug which is a cannabinoid receptor agonist developed by Bayer AG. It has analgesic and neuroprotective effects and is used in scientific research, with proposed uses in the treatment of traumatic brain injury.
It has analgesic and neuroprotective effects and is used in scientific research, with proposed uses in the treatment of traumatic brain injury. It is a full agonist with around the same potency as CP 55,940 in animal studies, and has fairly high affinity for both CB1 and CB2 receptors, with Ki values of 2.91nM at CB1 and 4.24nM at CB2. It has been licensed to KeyNeurotek Pharmaceuticals for clinical development, and is currently in Phase II trials.But its development appears has stopped.
Buy BB-22 Online$246.50 – $2,941.00
Buy BB-22 Online This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO17025 and Guide 34 guidelines. These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. All traceable RMs may be distinguished by their CofAs and can be downloaded below using the batch number located on the product label. For a representative CofA please contact our technical support.
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FAB-144 is an indazole-based synthetic cannabinoid that is presumed to be a potent agonist of the CB1 receptor and has been sold online as a designer drug. It is the indazole analogue of XLR-11. FAB-144 is an analogue of XLR-11, which acts like a potent agonist for the cannbinoid receptors. The CB1 and CB2 receptors offer a Ki of 24.2nM along with an EC50 of 359nM at CB1. It is an indole derivate, which is related to other compound including A-834,735 and A-796,260.
Buy FUB-AEB Online$208.00 – $2,960.00
This product is a qualified Reference Material (RM) that has been manufactured and tested to meet ISO17025 and Guide 34 guidelines. These materials are tested using validated analytical methods on qualified instrumentation to ensure traceability of measurements. All traceable RMs may be distinguished by their CofAs and can be downloaded below using the batch number located on the product label. For a representative CofA please contact our technical support.
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Buy MA-CHMINACA Online$252.00 – $4,920.00
AB-CHMINACA is an indazole-based synthetic cannabinoid (CB) that is structurally related to AB-FUBINACA , a high affinity ligand of the CB1 receptor (Ki = 0.9 nM).1,2 AB-CHMINACA metabolite M2 is a potential derivative resulting from the replacement of a terminal amide NH2 with a hydroxyl group. MA-CHMINACA is an analog of AB-CHMINACA metabolite M2 in which the hydroxyl moiety is replaced with a methyl ester group. The physiological and toxicological properties of this compound are not known. This product is intended for forensic and research applications.
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5F-MDMB-2201 is a synthetic cannabinoid (indazole family) very similar with MMB-2201. 5F-MDMB-2201 has very powerful action (agonism) at both the CB1 and CB2 receptors.
Systematic name: methyl 2-(1-(5-fluoropentyl)-1H-indole-3-carboxamido)-3,3-dimethylbutanoate
MMB-2201 is a potent indole-3-carboxamide based synthetic cannabinoid, which has been sold as a designer drug and as an active ingredient in synthetic cannabis blends.
Buy MDMB-CHMICA OnlineSale! $130.00 – $2,700.00
Several commercial samples of MDMB-CHMICA were found to exclusively contain the (S)-enantiomer based on vibrational and electronic circular dichroism spectroscopy and X-ray crystallography. An (S)-configuration for the tert-leucinate group is unsurprising since MDMB-CHMICA is likely synthesized from the abundant and inexpensive “L” form of the appropriate tert-leucinate reactant.
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MDMB-FUBINACA (also known as MDMB(N)-Bz-F and FUB-MDMB) is an indazole-based synthetic cannabinoid that is a potent agonist for the cannabinoid receptors, with Ki values of 1.14 nM at CB1 and 0.1228 nM at CB2 and EC50 values of 0.2668 nM at CB1 and 0.1411 nM at CB2, and has been sold online as a designer drug.Its benzyl analogue (instead of 4-fluorobenzyl) has been reported to be a potent agonist for the CB1 receptor (Ki = 0.14 nM, EC50 = 2.42 nM).The structure of MDMB-FUBINACA contains the amino acid 3-methylvaline or tert-leucine methyl ester.
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It was first reported in Russia and Belarus in January 2014, but has since been sold in a number of other countries. It is the indole core analogue of 5F-AMB. Synthetic cannabinoid compounds with an indole-3-carboxamide or indazole-3-carboxamide core bearing a N-1-methoxycarbonyl group with attached isopropyl or t-butyl substituent, have proved to be much more dangerous than older synthetic cannabinoid compounds previously reported, and have been linked to a large number of deaths in Russia, Japan, Europe and the United States