DICLAZEPAM (1 mg / Pellet) is the short name for 7-chloro-5-(2-chlorophenyl)-1-methyl-1,3-dihydro-2H-1,4-benzodiazepin-2-one and can be considered both to be the 2′-chloro analogue of diazepam or the 1-methyl analogue of Delorazepam.
As with all the chemicals that we stock, Diclazepam is not approved for any type of in-vivo research (i.e. not in humans or animals) or for clinical trials and therefore if accidently ingested then immediate medical attention should be sought. Please ensure you adhere to standard laboratory safety practices including using suitable skin, eye and clothing protection.
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Diclazepam is basically a synthetic depressant substance that belongs to a chemical class of benzodiazapines, and is related to diazepam in its properties.
The benzodiazepines contain a basic benzene ring that is linked with a seven membered diazepine ring, having two nitrogen constituents located at R1 and R4. Chemically, the Diclazepam has same structure, instead at R1 position, the Diclazepam is replaced with a methyl group.
The benzodiazepine ring is linked to a ring of 2-chlorinated phenyl at R5, and also a chlorine group is attached at R7 of benzyl ring. The Diclazepam also contains a ketone group that is formed by the double bonding of oxygen group to diazepine ring at R2 position.
This characteristic oxygen substitution at R2 position is similar in all benzodiazepine drugs, hence the suffix –azepam is given to them.
In 1960 at Hoffman-La Roche, Leo Sternbach with his team work together to first conduct its synthesizes.